Chaeum Premium 2 Dermal FillerMedium-viscosity hyaluronic acid filler with 18.5% cross-linking density and BDDE residues <0.3ppmCryoLink™ Cross-linking TechnologyUtilizing patented low-temperature cross-linking (4°C for 48hrs) with 14-day dialysis purification, Chaeum Premium 2 achieves homogeneous gel structure (PDI <0.18) and endotoxin levels <0.03 EU/ml. Third-party validation confirms protein content <0.04% and BDDE residuals of 0.28ppm±0.02 (n=15 batches).Clinical AdvantagesOptimal ElasticityG’ value of 220Pa provides natural movement resistance (85% patient satisfaction)Precision FlowConstant extrusion force 8.5N±0.3 enables smooth mid-dermal placementSafety Profile0.02% adverse event rate in 12-month follow-up (n=1,200 cases)Longevity9-12 month duration in 78% subjects (18-month multicenter study)Product SpecificationsComposition: HA 20 mg/ml Lidocaine 0.3%Cross-linking: 18.5% (CryoLink™ Technology)Needle: 27G×1/2″ (4 needles/pack)Volume: 2×1.1ml sterile syringespH: 6.8-7.2 (ISO 10993 compliant)Shelf Life: 24 months at 2-25°CClinical ProtocolIndication: Mid-to-superficial dermisAreas: Lips, Perioral, Periocular (Zone 1-2)Technique: Serial puncture or linear threadingDepth: 1.5-2.5mm dermal layerMax Dose: 1.5ml per sessionTouch-up: ≥2 weeks intervalApplication GuidelinesLip AugmentationFor vermillion border: 0.01-0.03ml per injection point using 27G needle. Maximum 0.6ml per lip quadrant.Glabellar LinesFor frown lines: 0.02ml aliquots at 5mm intervals. Maximum 0.4ml per treatment session.Crow’s FeetLateral canthus injection: 30° angle entry, 0.01ml per depot. Maximum 0.3ml per orbital zone.Medical NoticeImportant: Individual results may vary based on tissue elasticity and injection technique. Strict contraindications include: active herpes infection, history of keloid formation, and hypersensitivity to gram-positive bacterial proteins.Must be administered by certified practitioners with advanced facial anatomy training. Avoid intravascular injection through aspiration test. Post-treatment cold compress recommended for first 48 hours. Product stability guaranteed only when stored in original packaging.
